What is the composition of this smart drug?
This drug is a crystalline powder which is white to off-white in color and very slightly soluble in water. This is also slightly soluble in acetone and little soluble in methanol. The strength of this pill is 50mg 150mg or 250mg of Armodafinil. This pill does not bind or it does not inhibit receptors and enzymes that are potentially required for sleep regulations including those for serotonin, melatonin, dopamine, adenosine, galanin.
The inactive ingredients present in this drug are croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, and pregelatinized starch. These inactive ingredients are present along with different dosage strength of armodafinil.
What is the dosage structure of this drug?
Dosage structure for Obstructive Sleep Apnea (OSA) and Narcolepsy
The suggested dosage of armodafinil for patients with OSA or narcolepsy is 150 mg to 250 mg that is supposed to be taken orally once a day in the morning as a single dosage. In patients with OSA, if doses up to 250 mg/day have been properly tolerated and no-effects are seen then it will be required to increase the dosage after consulting the doctor.
Dosage structure for Shift Work Disorder (SWD)
The recommended dosage of armodafinil or nuvigil for patients with SWD is 150 mg that needs to be taken orally once a day approximately 1 hour preceding to the shift work. The gap should not increase in any way.
Those patients who are suffering from the severe hepatic impairments should make sure that they decrease the dosage of this Nuvigil drug.
Use in Geriatric Patients should be done by giving them low doses in the first instance and then slowly increasing the dosage of the drug.
Mechanism of action
The mechanism(s) through which armodafinil helps in promoting wakefulness is not known but Armodafinil (R-modafinil) has pharmacological properties that are similar to those of modafinil.
Armodafinil, as well as modafinil, has wakefulness promoting actions that are similar to sympathomimetic agents that includes amphetamine and methylphenidate, but the pharmacologic profile of armodafinil is not identical to that of the sympathomimetic amines.
Armodafinil has the properties and works like indirect dopamine receptor agonist. Both armodafinil and modafinil work similarly by binding to the dopamine transporter and inhibit dopamine reuptake.
The active component of NUVIGIL is armodafinil, which is comparatively longer-lived enantiomer of modafinil. NUVIGIL exhibits linear time-independent kinetics that is followed by single and multiple oral dose administration. Facing increased systemic exposure is over the dose range of 50 to 400 mg.
NUVIGIL is readily absorbed when taken orally. Peak plasma concentrations are seen to attain at approximately 2 hours after taking the medication in the state of fast. Effect of food on the absorption is minimal but if the drug is taken in a filled state then it may be delayed to 2- 4 hours.
Nuvigil has minimal reactions with highly protein-bound drugs but modafinil is moderately bound to plasma protein (approximately 60%), mainly to albumin.
NUVIGIL is contraindicated in patients who are allergic to modafinil and armodafinil or to any of its inactive ingredients. This drug has a few contraindications which a person should check with the online health expert before they online buy armodafinil.
You need to inform the doctor beforehand if you are suffering from any of the problems prior to taking this drug.
Side effects of armodafinil
Few of the patients have reported suffering from the few side-effects that are nausea, headache, nervousness, dizziness or having a problem with sleeping.
You need to inform the doctor immediately if you are suffering from any problem related to any problem of brain health changes, hallucination, depression, confusion, agitation, any thoughts of suicide or suicidal tendency or suffering from the problem of irregular heartbeat changes in mood or mental changes.
You can also suffer from serious allergic reaction like fever, swollen lymph, rash, itching and swelling especially in the face, tongue, throat, severe dizziness, trouble breathing.
Interactions of this drug
Before you buy armodafinil online you should be aware of the drug interaction with any of the medication.
This drug may react with the birth control hormonal pills that one is taking and it may also react with the vaginal ring or the patches that may be used during this time. You need to take some other methods of birth control by talking to your doctor as this may lead to pregnancy in future.
For all those women who are breastfeeding it is required to talk to the doctor and talk about the breastfeeding methods while taking this drug as it is not known how this will harm the infant and whether it passes to the breast milk or not.
Caffeine and chocolate can increase the side-effect of this drug and hence is not supposed to be taken along with this medication.
There may be some ingredients that may result to increase in the heartbeat or blood pressure. You need to especially tell your doctor if you are taking any medicines for treating cough or cold.
Effects of missed dosage
If you have missed any dose of armodafinil then you should take the dosage as soon as you remember and if it’s time for your next dose then you should leave the dose that you have missed and take the next dosage.
Effects of overdosage
There are no serious side-effects that have been reported in cases of overdosage but in case you have taken overdoses and suffering from trouble breathing you can call your nearest health line emergency number.