What is the chemical composition of memantine hydrochloride?
The chemical name of this memantine hydrochloride drug is 1-amino-3, 5-dimethyladamantane hydrochloride. The molecular formula of this drug is C12H21N•HCl and the molecular weight is 215.76. Memantine HCl is found in color white to off-white powder that is highly soluble in water.
Memantine HCl is available in the form of tablets or capsules with film coating or as an oral solution. The film coated capsule sized memantine HCL contains 5 mg to 10 mg of memantine hydrochloride
The tablets are formulated with the inactive ingredients along with the main ingredient that is lactose monohydrate, microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate and talc. In addition, there is other inactive ingredients that are present in the film coating hypromellose, iron oxide black (10 mg tablets), titanium dioxide, triacetin, FD&C blue (5 mg tablets) and FD&C yellow.
In each ml of this oral solution there is 2mg of memantine hydrochloride. The inactive ingredients present in this solution are sorbitol solution (70%), Propylparaben, Methylparaben, propylene glycol, glycerin, citric acid, sodium citrate, natural peppermint flavor and purified water.
What is the action mechanism of this drug?
Continuous and regular activation on the central nervous system by N-methyl-D-aspartate (NMDA) receptors with the help of excitatory amino acid glutamate leads to the problem of Alzheimer’s disease. This drug stops the reach of the glutamate to the brain as this glutamate substance is the main cause of Alzheimer’s disease. Before you buy memantine HCL online you need to make sure that you have consulted your physician.
There has been no evidence that memantine has ever prevented or slowed neuro degeneration in patients suffering from Alzheimer’s disease.
Memantine has shown low to minor connection to GABA, benzodiazepine, dopamine, adrenergic, histamine, and glycine receptors.
Pharmacokinetics of this drug
This drug, when taken orally, absorbs well in the blood and has linear pharmacokinetics over the curative dose range. This drug parts are excreted in the urine that remains unchanged and posses an ending half-life of about 60-80 hours.
Absorption and distribution
With oral administration, this drug has seen to be highly absorbed with peak concentrations level reaching in 3-7 hours. Food does not alter the absorption of memantine. The plasma protein binding of this drug is low that is 45%
Elimination and metabolism
Memantine shows very little metabolism, with the majority (57-82%) of the taken dose is excreted unchanged in through urine the remaining medication is changed to three polar metabolites that are N-gludantan conjugate, 6-hydroxy memantine, and 1-nitroso-deaminated memantine.
Memantine hydrochloride is a contraction for patients who are hypersensitive to memantine hydrochloride or to any other inactive ingredients present in the formulation of this drug.
What is the dosage structure of this drug?
This drug should not be taken without the proper prescription of the doctor. This drug can be taken with food or without food or as directed by the physician. Normally to allow the resistance of the drug and to avoid any side-effects this drug is given to be started from the lowest dosage. The dosages vary as per the response to the medication and the medical condition or health or severity of disease of the patient. This drug should be swallowed as a whole with water.
Take the medication exactly as directed by your doctor.
The prescribed dosage of every adult is 20 mg per day, which can be either taken as two separate doses of 10 mg once in the morning and 10 mg in the noon. Before you buy online memantine HCL you should be aware about the dosage that you are supposed to take consulting the doctor.
To avoid the risk of side-effects the doctor will gradually increase to 20 mg dose that depends on the person’s response to the medication. The time interval to be maintained by increasing the dose is one week.
You should not change the dosage of the medication, till the doctor has prescribed for it.
You should not chew the medication but take it as a whole with a glass of water.
You should not abruptly stop taking the medication before stopping it, you need to consult the doctor on how you can change the medication dosages. If you notice any abnormal allergic reaction immediately inform the doctor.
Unless you don’t find any health issue you can continue taking the medication.
What should one do in case of missed dosage?
You should not consume any pills of this drug if you find it tampers in anyways or if it’s damaged.
If you ever forget to take any dose of memantine HCl, in that case, you should not take one pill extra with the next dose. You should always take scheduled doses only. If by any chance you forget to take and you remember it within few hours of the gap, in that case, you can take then and there itself.
If you have taken the prescribed doses for several days in that case you should stop taking the doses any further until you consult with the doctor.
How to take care of overdosage?
Well, it has still not been confirmed about the effects of overdosages but in such case, you can always call the health center or you can visit your nearest health clinic or you can also call the poison center.
One thing you should always keep in mind that this should not be taken along with any kind of alcohol or any antidiabetic medications as this may cause serious problems like agitation, asthenia, bradycardia, coma, confusion, ECG changes, increase blood pressure, dizziness, lethargy, unconsciousness, stupor, psychosis, unsteady gait, vertigo, visual hallucination, restlessness, vomiting, slowed movement, weakness or somnolence. Before you buy online memantine you should check all the pros and cons of this drug.
What are the side effects of memantine drug?
The side- effects of this are not know as yet but the most common side effects of this drug include confusion, dizziness, headache, constipation. Other effects such as hypertension, high blood pressure, vomiting, anxiety, sleep disorder, hallucination may also happen. In case you are suffering from epileptic seizures then, in that case, there are minor changes to this drug to increase your problems.
How to store this medication?
Memantine should be always stored in room temperature between 59°F to 77°F (15°C to 30°C)
It should be kept out of children’s reach.
How can I buy memantine HCL medication online?
If someone wants to order memantine online then he needs to get a doctor’s prescription which confirms Alzheimer’s disease then only you can order this medication. You should never recommend someone this medication on your own who is suffering from similar problems unless he gets it prescribed by a doctor confirming his disease.